DOWNSTREAM INNOVATION
Leads To A New Level
Column Chromatography
Column-Less Technology
Our Column-Less technology makes a paradigm shift in mAb purification, significantly slashing both equipment costs and production time.
We have designed an innovative platform that achieved unparalleled productivity to break through the bottlenecks in downstream bioprocessing.
This technology lets you achieve process optimization by consolidating four chromatography units, including centrifuge, clarification filtration, in-line buffer preparation and chromatography columns.
Intensified process and
productive platform
SAVE YOUR
cost, time
and space
Streamlined Performance,
Dependable Outcomes
Initial Cost
-50%
Consumables*
-80%
Footprint
-70%
Processing time
5 Days 1 Day
Need more details or have questions?
CONTACT USDisclaimer: Our company’s research findings
are provided for informational purposes only.
*Consumables refer to resin usage.
CONTINUOUS
PURIFICATION PROCESS
CLEANING
It efficiently purges impurities from the resin.
ELUTION
Antibodies are isolated and collected from the resin in this step.
RESIN REGENERATION
Automatic resin regeneration is a hallmark feature of our column-less system, ensuring seamless operation.
CORE TECHNOLOGY
Static Mixer
- Work with no moving parts
- Mixing through water flow
- Complex structure achieve sufficient capturing
- No risk of contamination / In-line capturing
- Antibody capturing rate: 88%
Cyclone Separator
- Work with no moving parts
- Generating the downstream swirling flow collecting heavy sludge and upstream straight flow discharging light particles and liquid
- The dedicated shape purpose-built for the antibody capturing
- No risk of Contamination / In-line separation
- Resin recovery rate: 91%
EQUIPMENT
SPECIFICATIONS
EQUIPMENT SIZE
( H x W x D )
1931 x 1400 x 1267 mm
( 76.02 x 55.12 x 49.89 inches )
PROCESS SPECIFICATIONS
Applicable Bioreactor Volume: 50 ~ 500 L
System Flow Rates: 2,000 mL/min
Total Processing Times: 50 min/50 L ~ 500 min/500 L *1
*1 Average estimate time of antibody purification
SINGLE-USE KIT
External components are designed for single-use kits to increase productivity and reduce contamination risk.
RESINS
We developed dedicated Protein A resin that enables capturing in a short time. It is different from the conventional resins for chromatography columns, and it realizes a completely new affinity chromatography.